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Vancomycin can cause two types of hypersensitivity reactions, the red man syndrome and anaphylaxis. Red man syndrome has often been associated with rapid infusion of the first dose flusihng the drug and was initially attributed to impurities found in vancomycin preparations. Even after improvement in paves purity, however, reports of the syndrome persist. Other antibiotics e. Discontinuation of the vancomycin infusion and Sexy asian Danmark of diphenhydramine can abort most of the reactions. Slow intravenous administration of vancomycin should minimize the risk of infusion-related adverse effects.

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